李礼，男，1981年9月出生，国家优秀青年科学基金获得者。2000-2005年在复旦大学获得学士学位，2007-2011年在香港科技大学获得博士学位。2012年至2021年任西南大学生命科学学院研究员和博士生导师，2021年起兼任西南大学发育生物学与再生医学研究中心研究员。中国细胞生物学学会理事、中国生理学会血液生理学专业委员会委员。课题组以斑马鱼和小鼠为模式动物，围绕着造血干细胞稳态维持、分化及免疫细胞在器官衰老中的功能等开展研究，同时基于疾病模型进行高通量药物筛选。先后在Immunity, PNAS, Blood，Leukemia, J Biol Chem等国外知名学术期刊发表论文十余篇。近年来获得“国家优秀青年科学基金项目”、“国家自然科学基金面上项目”、 “国家重点研发计划”项目课题等科研基金的资助。入选重庆市青年专家工作室领衔专家，重庆市青年拔尖人才等资助项目。
主要论著：
1. Fangying Zhao, Yafang Lu, Zhifan Li, Jiangyong He, Nianfei Cui, Lingfei Luo, Li Li* (2022) CXCR4-CXCL12 axis promotes T-cell reconstitution via efficient hematopoietic immigration. Journal of Genetics and Genomics. In press.
2. Dandan Zou , Wenlong Hu , Jie Qin, Zongfang Wei, Danyang Wang , Li Li*.(2021) Rapid orderly migration of neutrophils after traumatic brain injury depends on MMP9/13. Biochem Biophys Res Commun. 2021 Nov 19;579:161-167.
3. Zhi Feng, Chenyu Lin, Limei Tu, Ming Su, Chunyu Song, Shengnan Liu, Michael Edbert Suryanto, Chung-Der Hsiao*, Li Li*. (2021) FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish. Cells. Aug 20;10(8):2149. doi: 10.3390/cells10082149.
4. Zongfang Wei, Chenzheng Li, Yangping Zhang, Chenyu Lin, Yiyue Zhang, Liping Shu, Lingfei Luo, Jian Zhuo*, and Li Li*. (2020) Macrophage derived IL-1β regulates emergency myelopoiesis via the NF-κB and C/ebpβ in zebrafish. The Journal of Immunology. Nov 15; 205(10):2694-2706
5. Huang Y, Lu Y, He Y, Feng Z, Zhan Y, Huang X, Liu Q, Zhang J, Li H, Huang H, Ma M, Luo L, and Li L*.(2019) Ikzf1 regulates embryonic T lymphopoiesis via Ccr9 & Irf4 in zebrafish. Journal of Biological Chemistry. Nov 1;294(44):16152-16163
6. Huang W, Liu Z, Yang F, Zhou H, Yong X, Yang X, Zhou Y, Xue L, Zhang Y, Liu D, Meng W, Zhang W, Zhang X, Shen X, Sun Q, Li L, Ma C, Wei Y, Billadeau DD, Mo X, Jia D*.(2019) Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH. Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22598-22608.
7. Zhan Y, Huang Y, Chen J, Cao Z,He J, Zhang J, Huang H, Ruan H, Luo L,* and Li L*. (2018) The caudal dorsal artery generates the hematopoietic stem and progenitor cells via the endothelial-to-hematopoietic transition in zebrafish. Journal of Genetics and Genomics. 45(6):315-324
8. Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L, Li L*. (2018)Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia.32 (1): 149-158
9. Yu T, Guo W, Tian Y, Xu J, Chen J, Li L, Wen Z* (2017) Distinct regulatory networks control the development of macrophages of different origins in zebrafish. Blood 129(4):509-519.
10. Liu C, Wu C, Yang Q, Gao J, Li L, Yang D, Luo L*. (2016) Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction. Immunity. 17;44(5):1162-76.
*：通讯作者